I have applied kambo to 3 people so far, and the person who seemed to benefit most from it is a Buddhist monk. He liked it a lot and says that he can feel its energy entering him through the top of his head which is interesting. He was far more sensitive to it than the other two people who I applied it to. I also noted that out of the 3 people I applied it to, the two more spiritually inclined people purged. All 3 of these people are on a spiritual path, and I deemed them worthy to receive the medicine as they naturally have a respect for it, but it seems that the more deeply spiritually inclined the person is, the more sensitive they are to the medicine.