Classes of Plant Constituents > Alkaloidology
Honokiol & Magnolol from Magnolia
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Honokiol induces reactive oxygen species-mediated apoptosis in Candida albicans through mitochondrial dysfunction
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172228
The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors.
https://www.ncbi.nlm.nih.gov/pubmed/22445602
Honokiol, a putative anxiolytic agent extracted from magnolia bark, has no diazepam-like side-effects in mice
https://www.ncbi.nlm.nih.gov/pubmed/10197425
Magnolol and honokiol isolated from Magnolia officinalis protect rat heart mitochondria against lipid peroxidation.
https://www.ncbi.nlm.nih.gov/pubmed/8117323
Honokiol targets mitochondria to halt cancer progression and metastasis.
https://www.ncbi.nlm.nih.gov/pubmed/27276215
University of Alabama at Birmingham found the compound - honokiol - blocked a protein that drives tumor growth in squamous cell head and neck cancers
http://www.medicalnewstoday.com/articles/295962.php
Honokiol Ameliorates Amyloidosis and Neuroinflammation and Improves Cognitive Impairment in Alzheimer's Disease Transgenic Mice.
https://www.ncbi.nlm.nih.gov/pubmed/29991481
Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55.
https://www.ncbi.nlm.nih.gov/pubmed/24900561
SIRT3 activator Honokiol attenuates β-Amyloid by modulating amyloidogenic pathway
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190350
Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents.
https://www.ncbi.nlm.nih.gov/pubmed/18093712
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