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PharmacologyThe hypoglycemic activity of alkaloids isolated from Catharanthus roseus have been studied pharmacologically and a natural remedy derived from the plant has been marketed under the proprietary name Vinculin® as a treatment for diabetes.Alcoholic whole plant extracts at high dose (500 mg/kg) exhibited significant antihyperglycemic activity and has absence of acute toxicity. The extract effectively reverses the changes in the blood sugar level and the beta-cell population. The exact phytoconstituents responsible for the antidiabetic effect are not known yet.
Catharanthus roseusDon, also known as Vinca, which is used by the population in Madagascar in treating diabetes.