Wild Dagga (Leonotis leonurus)
Method of Use: Smoke, Chew, Tea
Classification: Hypnotic, Sedative
Classification: Hallucinogen
Classification: Stimulant
Drug Effects: History of use in S Africa as a cannabis
substitute. The foliage is commonly made into a medicinal
tea, which is favoured for the hypnotic focus it gives
Short Term Effects: Calming, euphoric marijuana-like
experience, higher appreciation of soft things, relaxing of
muscles & cns, reduce fatigue
Long Term Effects: Antirheumatic, expectorant, vermifuge, antispasmodic, antihistamine
Negative/Overdose Risk: Diarrhea, dizziness, nausea, sweat inducing
Dependency: For some people can be as addictive as tobacco
Withdrawal: No real withdrawal symptoms
Active Constituents: (E)-Beta-Farnesene, (E)-Beta-Ocimene, (Z)-Beta-Farnesene, (Z)-Beta-Ocimene, 2-Pentyl-
Furan, Allo-Ocimene, Alpha-Cadinol, Alpha-Copaene, Alpha-Cubebene, Alpha-P-Dimethyl-Styrene, Alpha-Pinene,
Alpha-Thujene, Beta-Bourbonene, Beta-Caryophyllene, Beta-Cubebene, Beta-Myrcene, Borneol, Calamenene,
Caryophyllene-Oxide, Delta-Terpineol, Gamma-Muurolene, Leonitin, Leonurine, Limonene, Linalol, Marrubiin,
P-Cymen-8-Ol, P-Cymene, Premarrubiin, Quinones, Resin, Sabinene, Saponin, Spathulenol, Tannins.
Contraindications / Interactions: Not recommended for use by pregnant women[/color][/glow]
Info from
Psychoactive Substances: A Guide to Ethnobotanical Plants and Herbs, Synthetic Chemicals, Compounds and Products
MAOI:Family Species Plant part Extract Non-selective MAO inhibition IC50 (μg/ml)a Selective MAO-B inhibition IC50 (μg/ml)a,b
Leonotis leonurus Leaf Water 1110 ± 147 345 ± 399
Leaf Ethanol 63 ± 12 nt
a
IC50 and standard error calculated using Grafit 5 (© Erithacus Software Limited). Extract concentration in (μg/ml) and standard reference drugs in nanomolar.
b
Activity not detected — nd, extract not tested — nt.
Monoamine oxidase inhibition by southern African traditional medicinal plantshttps://www.sciencedirect.com/science/article/pii/S0254629907002128#tblfn1
