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Topics - ―λlτεrηιτγ-

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3
Experimental Research / Red Light Therapy
« on: December 12, 2020, 07:18:31 am »
Red light therapy treats pain relief, wound healing, anxiety/depression, hair loss, weight loss, wound healing, fibromyalga, muscle pain, fatigue, skincare, and acne.
It is anti-aging and increases cognitive performance,
They sell cheap led light strips with a remote that goes around the top of your walls.
They can be used for green light and red light therapy.

4
General Discussion / Nitrogen & Oxygen
« on: December 12, 2020, 07:01:43 am »
Quote
How It Works
Your body needs the nitrogen in amino acids from protein foods to make other amino acids it uses to synthesize human proteins, according to Virtual Chembook at Elmhurst College. Not only do your various tissues contain protein, your metabolic processes depend upon enzymes, all of which consist of various kinds of proteins. The nucleic acid DNA, which makes up your genes, and RNA, which is involved in protein synthesis, also contain nitrogen.

Features
Normal growth, cell replacement and tissue repair all require nitrogen for production of new cells. Although nitrogen is abundant in the environment, humans cannot directly use it from the air or soil, but instead depend on microbes and green plants to convert it into form our bodies can use. Your body is constantly recycling nitrogen from amino acids. If amino acids are not used for protein synthesis, they can be broken into components, including nitrogen, to produce energy. Nitrogen can also be used to make other types of compounds that aren't proteins, such as the heme in hemoglobin, which carries oxygen in red blood cells.

Requirements
A healthy adult male needs about 105 milligrams of nitrogen per kilogram, or per 2.2 pounds per day. About 0.83 gram of protein per kilogram per day is considered sufficient to cover nitrogen requirements, according to the International Dairy Foundation. That means a 220-pound man would need 83 grams, or about 3 ounces, of protein a day to supply his nitrogen needs. The breakdown of protein results in ammonia, a nitrogen-containing byproduct that your body eliminates.

Additional Information
Your body eliminates ammonia by converting it to urea, which your kidneys then excrete in urine. In this way, nitrogen is returned to the environment. Unlike populations in underdeveloped countries, Americans do not commonly suffer from a lack of dietary nitrogen unless they are on extreme diets that do not contain sufficient protein. Symptoms of deficiency include hair loss, delayed wound healing, muscle weakness and wasting, brittle hair and hair loss.

Nitrogen in molecules help them to cross the blood-brain barrier,
so I feel like the reason Nitrous Oxide (2 nitrogen atoms attached to an oxygen atom) is so euphoric is cause oxygen is a painkiller and
Quote
"Pain is a lack of oxygen at the cellular level." While I'm not sure this is always true, I believe that in most cases pain is caused by a lack of oxygen reaching the tissues. Usually pain is caused by inflammation, which is the normal response to tissue damage.
Quote
Oxygen should be viewed as a drug. Remember that the difference between therapeutic and toxic is the dose. Chest pain is not an indication for oxygen administration.

I feel like increased oxygen in the air would kill pain and be anti-depressant and anxiolytic.
Since humans started on earth we lost most of the world's plants.
They are what convert our carbon dioxide to oxygen,
so all people should grow plants.
Like pets, they can bring enjoyment.

5
General Discussion / News
« on: December 11, 2020, 09:28:18 pm »
I'm sorry that I have been away.
I could not log into the site;
And I just got my laptop back from the shop, which was out of commission since around the end of May / beginning of June?
I still need another admin to fix my password for me so I can create new topics and such.
I will be continuing to update the site and make posts.
As well as deleting all the bullshit posts from new users with a 1 or 2 post count, that are nonsensical posts to advertise links in their signatures.
Posts of this kind will be removed.

I hope everyone continues visiting back.
If you enjoy reading this website, thank you for the support.
If you can contribute to the forum and start conversations, I encourage you to sign up and post.

Kind regards

9
Supplements / Lithium
« on: January 19, 2020, 06:27:46 pm »
Oxidative metabolism
Quote
Evidence suggests that mitochondrial dysfunction is present in patients with bipolar disorder.[72] Oxidative stress and reduced levels of anti-oxidants (such as glutathione) lead to cell death. Lithium may protect against oxidative stress by up-regulating complex I and II of the mitochondrial electron transport chain.

Dopamine and G-protein coupling
Quote
During mania, there is an increase in neurotransmission of dopamine that causes a secondary homeostatic down-regulation, resulting in decreased neurotransmission of dopamine, which can cause depression.[72] Additionally, the post-synaptic actions of dopamine are mediated through G-protein coupled receptors. Once dopamine is coupled to the G-protein receptors, it stimulates other secondary messenger systems that modulate neurotransmission. Studies found that in autopsies (which do not necessarily reflect living people), people with bipolar disorder had increased G-protein coupling compared to people without bipolar disorder.[72] Lithium treatment alters the function of certain subunits of the dopamine associated G-protein, which may be part of its mechanism of action.

Glutamate and NMDA receptors
Quote
Glutamate levels are observed to be elevated during mania. Lithium is thought to provide long-term mood stabilization and have anti-manic properties by modulating glutamate levels.[72] It is proposed that lithium competes with magnesium for binding to NMDA glutamate receptor, increasing the availability of glutamate in post-synaptic neurons.[72] The NMDA receptor is also affected by other neurotransmitters such as serotonin and dopamine. Effects observed appear exclusive to lithium and have not been observed by other monovalent ions such as rubidium and caesium.

GABA receptors
Quote
GABA is an inhibitory neurotransmitter that plays an important role in regulating dopamine and glutamate neurotransmission.[72] It was found that patients with bipolar disorder had lower GABA levels, which results in excitotoxicity and can cause apoptosis (cell loss). Lithium has been shown to increase the level of GABA in plasma and cerebral spinal fluid.[74] Lithium counteracts these degrading processes by decreasing pro-apoptotic proteins and stimulating release of neuroprotective proteins.[72] Lithium's regulation of both excitatory dopaminergic and glutamatergic systems through GABA may play a role in its mood stabilizing effects.

Cyclic AMP secondary messengers
Quote
Lithium's therapeutic effects are thought to be partially attributable to its interactions with several signal transduction mechanisms.[76][77] The cyclic AMP secondary messenger system is shown to be modulated by lithium. Lithium was found to increase the basal levels of cyclic AMP but impair receptor coupled stimulation of cyclic AMP production.[72] It is hypothesized that the dual effects of lithium are due to the inhibition of G-proteins that mediate cyclic AMP production.[72] Over a long period of lithium treatment, cyclic AMP and adenylate cyclase levels are further changed by gene transcription factors.

Inositol depletion hypothesis
Quote
Lithium treatment has been found to inhibit the enzyme inositol monophosphatase, involved in degrading inositol monophosphate to inositol required in PIP2 synthesis. This leads to lower levels of inositol triphosphate, created by decomposition of PIP2.[78] This effect has been suggested to be further enhanced with an inositol triphosphate reuptake inhibitor. Inositol disruptions have been linked to memory impairment and depression. It is known with good certainty that signals from the receptors coupled to the phosphoinositide signal transduction is affected by lithium.[79] myo-inositol is also regulated by the high affinity sodium mI transport system (SMIT). Lithium is hypothesized to inhibit mI entering the cells and mitigating the function of SMIT.[72] Reductions of cellular levels of myo-inositol results in the inhibition of the phosphoinositide cycle.

https://en.wikipedia.org/wiki/Lithium_(medication)#Glutamate_and_NMDA_receptors

10
General Discussion / Kambo.me URL working again.
« on: January 19, 2020, 05:18:30 pm »
Kambo.me URL is working again.

11
Video / Desert Seas
« on: January 18, 2020, 02:04:10 am »

12
Video / Mucky Secrets (Documentary)
« on: January 18, 2020, 02:01:20 am »
Let's bring in some nature documentaries.

Mucky Secrets (Documentary)

https://www.youtube.com/watch?v=nJMZ6reOB0E

15
When new Boards (sections) of the forum are added, the forum does not automatically add the base "membergroup":
"Called By The Medicines", the ability to access them.
Perhaps because when users sign up, they start off in that category and require no posts to access the forum.

What a shame because half the forum or more was blocked to yous.
I just manually added added (checked) that membergroup for access for every board on the forum.
Most all of you will now find a huge amount of new sections / topics.

Go here: http://kambo.me/smf/index.php

And just look while scrolling down. FYI you can customize by collapsing / minimizing sections that you don't visit.

Perhaps the Spanish section will be helpful to many that seem to struggle posting.

Please now - Everyone enjoy the rest of the forum!!

EDIT: Not sure the cause of this, if it was a forum glitch, in which case it should have been fixed.
It doesn't make sense cause even guests can view all the sections. Can anyone that is logged in, confirm that they were effected by this?


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