Kambo

Kambo To Prepare For An Iboga Full On Initiation (aka a Flood) => Kambo Preparation for the Pinnacle Spiritual Experience (Iboga flood) => Topic started by: peacefull warrior on December 03, 2012, 10:53:49 PM

Title: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on December 03, 2012, 10:53:49 PM
i will start with this short list then i will at some point in the future explain in a simple way why NMDA antagonists are beneficial for use with iboga and without.

zinc
magnesium
parsley
cats claw
garlic (a piece the size of an almond or two is enough, must be fresh and chewed and swallowed fast)
dxm
PEA (phenethylamine)

wikipedia has an extensive list that is missing a few of these.

most traditional psychedelics also antagonize NMDA

NMDA antagonists also cause the NMDA receptor to become upregulated when the antagonism wears off, this increases intelligence permanently.

in this thread i will explain the NMDA, kappa, dopamine, oxytocin, prolactin systems in short ad explain how they interact with one another. this info will be useful for things beyond iboga, so for threads about other topics just link them here.
Title: Re: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on February 08, 2013, 12:14:16 AM
i have recently found out that vitamins B12 and possibly B2 and another B vitamin are NMDA antagonists, this is great find as these are absolutely essential anyway.

Title: Re: NMDA antagonists (especially for iboga)
Post by: marypoppins on February 10, 2013, 01:31:01 AM
how would this work / effect / affect each other

ibogaine is an nmda antagonist and noopept is an nmda agonist ???????
Title: Re: NMDA antagonists (especially for iboga)
Post by: Xochipilli on July 15, 2013, 05:41:50 AM
I have heard good things about the synergy between iboga and NMDA antagonists too. Taurine is a mild NMDA antagonist. For prescription ones, I'd go with memantine or acopronsate.

Can you explain about the NMDA, kappa, dopamine, oxytocin and prolactin systems? Sounds really interesting, I'd love to know about this. Also, when you say NMDA upregulation causes a "permanent" increase in intelligence, do you mean due to formation of new neural pathways, or do you mean the upregulation of the receptors is permanent?
Title: Re: NMDA antagonists (especially for iboga)
Post by: Kambogahuasca Panacea on July 15, 2013, 09:42:20 PM
Might need to PM him (Peaceful Warrior), he no longer seems to post here. 
Title: Re: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on July 22, 2013, 07:38:20 PM
i still will be posting everywhere, we have to be careful about what, how much and how fast and to who we share.
Title: Re: NMDA antagonists (especially for iboga)
Post by: Xochipilli on August 02, 2013, 11:57:30 AM
Can you elaborate on your OP peacefull warrior? I study a fair bit of pharmacology (I'm a chemistry major) so I find it very interesting. The (majority at least) people on this forum are people with the sole intent to heal themselves and others, so if they are not the right people to share with, I don't know who is. Sharing information in order to empower each other with knowledge is what this forum is all about. When I'm talking to people who are in seek of new methods of healing themselves and others, I inform them in any way I can, because knowledge is power, and the knowledge you have, might give another person the power to heal themselves and their fellow man.

I have quite a bit of knowledge concerning the glutamatergic system and over the past few months have been attempting to develop methods to utilise the connection between glutamate receptors and synaptic plasticity to direct the process of neuroplasticity, which is something that could help alleviate a great amount of suffering in this world. I'm sure I will be able to contribute knowledge to this thread, if you elaborate on what it is about. Remember, NMDA isn't the only glutamate receptor. Great things are being accomplished via the development of allosteric modulators for the AMPA receptor.
Title: Re: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on August 02, 2013, 05:02:46 PM
yes sorry for the so frequent lapses of sharing, there are many things that pull me, i will be explaining things i have said in the past in more detail soon.

"allosteric modulators"

not to take away from any work being done, or to be done, but i like to think of substances as training tools to help teach how to use the respective systems with ones intent, will, etc etc

PAM and NAM are temporary as is ALMOST every substance related alteration i have found, even the ones that seem to be non temporary seem to have ways of showing the non permanence beneath all, transience takes all forms even permanence.
Title: Re: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on August 02, 2013, 11:42:48 PM
I have heard good things about the synergy between iboga and NMDA antagonists too. Taurine is a mild NMDA antagonist. For prescription ones, I'd go with memantine or acopronsate.

Can you explain about the NMDA, kappa, dopamine, oxytocin and prolactin systems? Sounds really interesting, I'd love to know about this. Also, when you say NMDA upregulation causes a "permanent" increase in intelligence, do you mean due to formation of new neural pathways, or do you mean the upregulation of the receptors is permanent?

"Taurine is a mild NMDA antagonist"

taurine is extremely dangerous and should be handled with extreme care if not avoided like the plague of death itself.

"when you say NMDA upregulation causes a "permanent" increase in intelligence, do you mean due to formation of new neural pathways, or do you mean the upregulation of the receptors is permanent?"

new pathways, and the upregulation that you get for a few days teaches the inner post-atomic memory system how to control the system without the need for external stimuli, that literally means its like getting function back to a paralyzed limb.

Title: Re: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on August 03, 2013, 01:15:47 PM
http://www.natural-health-zone.com/meridian-clock.html

its important you understand this chart before we go forward.

Title: Re: NMDA antagonists (especially for iboga)
Post by: ―λlτεrηιτγ- on August 04, 2013, 12:02:07 AM
Hello,

please provide evidence for this claim.

Quote
taurine is extremely dangerous and should be handled with extreme care if not avoided like the plague of death itself.

thanks
Title: Re: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on August 04, 2013, 09:00:03 AM
Hello,

please provide evidence for this claim.

Quote
taurine is extremely dangerous and should be handled with extreme care if not avoided like the plague of death itself.

thanks

ask kambo what he/she thinks of "taurine"
Title: Re: NMDA antagonists (especially for iboga)
Post by: ―λlτεrηιτγ- on August 05, 2013, 04:30:02 AM
Why don't you ask Kambo and get back to me.
Title: Re: NMDA antagonists (especially for iboga)
Post by: Kambogahuasca Panacea on August 05, 2013, 11:22:22 AM
I certainly don't want any drama here and blame no one for it occurring but if at all possible to remain civil (and not become like 99% of other forums).  So far we have been able to keep it real and immune here and I think it would be best if we kept it at that level. 

Especially PW if you have ideas if you can ground them as best as possible and not use the more celestial argument to ask the frog/Kambo.  That is in fact not a logical analysis and things need to be rooted in the earth with some clear explanation.  If you cannot do so then we can just move on and presume it was not a factual basis of reasoning.  If you have explanations for your findings than it is important to site sources and/or your intuitive reasonings.  Otherwise it comes off as insulting when you just reply like this...

Quote
ask kambo what he/she thinks of "taurine"

I don't mean to talk down to you but clearly this is not said in a friendly manner and what PC was trying to find is your evidence not just to ask Kambo (which would likely lead to many assumptions rather than one fact).  Glad to have you back around but please take time if you do write to bring some factual information.  We may be smart but we need some evidence to prove that you have adequate leads. 
Title: Re: NMDA antagonists (especially for iboga)
Post by: ―λlτεrηιτγ- on August 05, 2013, 11:36:57 AM
Yes, I spent $80 on a supplement last night with taurine. A workout stack which I love.
http://www.ebay.com/itm/EXTREME-NITRIC-STACK-KIWI-STRAWBERRY-1000-GRAMS-/320657262828

It states that Taurine

Improves cell volumization.
Aids in electrolyte balance.
Improves muscle growth processes.
Boosts protein synthesis.
Maintains glucose uptake.

I was hoping for some information before I went ahead and spent 80 bucks.
And even if I could count on a coherent explanation of taurines flaws or even an intuitive feeling by the Kambo spirit,
I'm not ready to consult Kambo right now but when the time is right.
If something is toxic, we should not withhold info on that and state to consult higher spirits about them.
Especially since these realms and abilities become harder to attain with a toxified body.
Title: Re: NMDA antagonists (especially for iboga)
Post by: Kambogahuasca Panacea on August 05, 2013, 11:49:47 AM
I would trust your own critical thinking skills and research ability before asking Kambo.  Personally when I ask Kambo something it is not going to be about Taurine, rather on my personally life and something really worth asking.  Taurine and it's benefits or harm is simple enough to find with a clear and tangible thought process.  I find Kambo likes just one question and not all sorts of questions, like "how can I be more still"? It can answer that but I find unless taking Ayahuasca or Iboga shortly thereafter Kambo is rather straight forward and doesn't like many questions.  When taking a sacrament IMO (other than Iboga) it is best to be as simple and clear as possible with as few questions as possible.  That way the intent is much easier to follow and recall.  Like when drinking Daime I have found my best intent 100% is just this, "Divine Mother teach me how to be closer to you"?  Troubles surmount (from the way I was taught) when meditating when one becomes overly complicated.  Simple and straight to the point will reveal answers in a way that makes sense. 

^Those are just my opinions to be taken with a grain of salt and just to add to the discussion not as a final say of authority and I hope it didn't come off like that, if so please feel free to say so and I will adjust my decorum.
Title: Re: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on August 05, 2013, 12:25:34 PM
taurine can do a lot of good to some people in some circumstances at some times.

make sure you do not take it with any sort of regularity.

every person has a different composition, what is a cure for you could be a poison for the next.
Title: Re: NMDA antagonists (especially for iboga)
Post by: peacefull warrior on August 05, 2013, 12:58:26 PM
"When taking a sacrament IMO (other than Iboga) it is best to be as simple and clear as possible with as few questions as possible"

i apologize, i should have recommended you ask iboga.
Title: Re: NMDA antagonists (especially for iboga)
Post by: ―λlτεrηιτγ- on August 05, 2013, 01:03:04 PM
Quote
^Those are just my opinions to be taken with a grain of salt and just to add to the discussion not as a final say of authority and I hope it didn't come off like that, if so please feel free to say so and I will adjust my decorum.

I agree with you.
Quote
..., rather on my personal life and something really worth asking.
Title: Re: NMDA antagonists (especially for iboga)
Post by: Xochipilli on August 10, 2013, 01:42:08 PM
not to take away from any work being done, or to be done, but i like to think of substances as training tools to help teach how to use the respective systems with ones intent, will, etc etc
Thats a cool way to think of it. I haven't figured out how to use my intent/will to replicate the effects of many substances though. I can enter a state similar to that induced by hapi and other dopamine releasing substances through meditation though, which is fairly interesting.

PAM and NAM are temporary as is ALMOST every substance related alteration i have found, even the ones that seem to be non temporary seem to have ways of showing the non permanence beneath all, transience takes all forms even permanence.
Thats how it goes. However, if a substance causes a new neural pathway to form, then it becomes natural to stimulate this neural pathway in ones every day state, this change will be permanent.

BTW lets not derail the thread into a discussion on taurine. Lets keep it focussed on NMDA antagonists in general, and related (in this context) classes of substances.

There is more to the anti addictive properties of NMDA antagonists than NMDA antagonism itself. Further down the metabolic cascade is the release of nitric oxide (i.e. NMDA activation leads to the synthesis and subsequent release of more nitric oxide) and nitric oxide inhibitors like methylene blue have similar anti addictive properties. I wonder if there are any natural NO inhibiting substances known.