331
Who can and can't do Kambo? / Re: Kambo and bio-identical hormonal replacement
« on: May 09, 2016, 11:56:11 AM »
Yup, I agree with everything you said including the salt. I enjoyed reading your posts. Please stick around!

Need more info? Ecosia Private Search - that plants trees!
Chatroom
Donate
This section allows you to view all posts made by this member. Note that you can only see posts made in areas you currently have access to.
the main issue here is that you are using a USA based top level domain (.org) and the reason why we are not using any USA based top level domain is that we do not want an extradition to the USA:
https://www.dmt-nexus.me/forum/default.aspx?g=posts&m=254448#post254448
So for this we cannot allow any USA based top level domains for any of our sites. I hope you understand.
p.s. I have made the original kambo.me page now go directly to kambo.me/smf
Kind regards,
The Traveler
It's selective estrogen receptor modulator (SERM) compounds were found to be non-estrogenic and anti-estrogenic at receptors in the hypothalmus, bone, liver, brain, and arteries primarily.
Synthetic SERMS are usually taken with prohormones and steroids by bodybuilders to minimize effects from excess testosterone being converted to estrogens.
Usually SERMs are estrogenic at some receptors and anti at others and the point is to get the benefits of estrogen and none of the negative effects by blocking the receptors from the free-flowing estrogens in the body. The fact that they bind at estrogen receptor sites still makes them estrogens (they still have estrogenic effects).
Natural black cohosh doesn't. It can be used all the time and to greater effect.
Black cohosh binds at these estrogen receptor sites but doesn't cause any estrogen-like effects and is anti-estrogenic, which would mean it would clean any natural estrogens in your body from effecting you by blocking the receptors. Like those artificial estrogens/hormone disrupters like those that are leached from plastic water bottles.
So I popped one pill, and awaited its effects. The effects came on relatively quickly. I felt slightly sedated, so I plopped on my bed for a nap.https://erowid.org/experiences/exp.php?ID=67354
I looked at the ceiling and the walls seem to be moving slightly, and it looked like my rods and cones were more visible than usual. Just minor benadryl-like hallucinations.
It reminded me of kava kava herb which is a sedative and mild psychedelic.
N-Methylserotonin. 5-Hydroxy-N-methyltryptamine.http://www.chemspider.com/Chemical-Structure.132989.html
NMT has been found in the bark, shoots and leaves of several plant species, including Virola, Acacia, Mimosa and Desmanthus
Orally administered NMT appears to produce no psychoactive effects, likely as a result of extensive first-pass metabolism.[3] However, it may become active upon combination with a MAOA inhibitor (MAOI).[3] By vaporization NMT shows activity at 50–100 mg, with a duration of 45–70 minutes; duration of visual effects 15–30 seconds. Effects are primarily non-visual.https://en.wikipedia.org/wiki/N-Methyltryptamine
Compound 53 had an elemental composition containing two hydrogens less than 58 and 59 (C12H12N2O), suggesting a dihydro-β-carboline structure. The ready loss of a methyl radical (m/z 186), along with the fragment ion of m/z 170, [MH-CH3NH2]+, indicated that the N(2) nitrogen on the β-carboline ring was methylated. Biosynthetic considerations were used to deduce the position of the double bond on the β-carboline ring. Accordingly, the most likely position of the double bond is 1,2 which was confirmed by comparison of retention time and fragmentation pattern with authentic N(2)-methyl-6-hydroxy-3,4-dihydro-β-carboline. Biosynthetically, this compound is likely formed by dehydrogenation of 58 and represents a new natural product. It should be noted that dihydro-β-carbolines are often by-products of Pictet-Spengler condensation [58]. Thus, it is possible that 58 is an isolation artifact.
The product ion spectrum of compound 46 eluting at 10.6 min during LC-MS of fraction 4 was dominated by an ion of m/z 144 with the elemental composition (C10H13N2), corresponding to protonated tryptamine. In-source fragmentation followed by MS-MS product ion analysis of m/z 144 showed a fragmentation pattern identical to authentic tryptamine, suggesting that this compound is a tryptamine derivative. The neutral loss of iminoacetic acid (C2H3NO2) combined with database searching suggested that 46 might be a tetrahydro-β-carboline carboxylic acid. Since two positional isomers (1 and 3-substituted) are known, both analogs were synthesized and compared with 46. These experiments identified 46 as 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341503/
Aporphine and its related alkaloids bulbocapnine, boldine, glaucine and corytuberine are antipsychotic, exert naloxone-reversible antinociceptive (reducing sensitivity to painful stimuli) activity and with the exception of corytuberine are anticonvulsant.https://en.wikipedia.org/wiki/Aporphine
In a rodent model, it was found that higenamine (norcoclaurine) produced cardiotonic, vascular relaxation, and bronchodilator effects.[8][9] In particular, higenamine, via a beta-adrenoceptor mechanism, induced relaxation in rat corpus cavernosum, leading to improved vasodilation and erectile function.https://en.wikipedia.org/wiki/Higenamine
Related to improved vasodilatory signals, higenamine has been shown in animal models to possess antiplatelet and antithrombotic activity via a cAMP-dependent pathway, suggesting higenamine may contribute to enhanced vasodilation and arterial integrity.[2][7][9][10]
Reticuline is one of the alkaloids found in opium, and experiments in rodents suggest it possesses potent central nervous system depressing effects.[3] It is the precursor of morphine and many other alkaloids.https://en.wikipedia.org/wiki/Reticuline