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Messages - Hip

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31
Application / Re: Kambo Snuff
« on: December 19, 2012, 12:46:17 AM »
My nostril burned intensely, though now it's fine. I'm a little concerned of its possible effects on the nasal region, though, given right now it's very clogged.

I look forward to your next report, kamamambo.

What I might do the next time I snort kambo is spray some normal saline solution (physiological solution) into my nose beforehand, using a nasal spray. This pre-wetting of the nasal cavity may cushion the blow that kambo has on the nasal mucosa.

32
Safety Warning
Danger of Death!

Just to be cautious, I have just written a safety warning about experimenting with alternative methods of taking kambo. This safety warning has been placed in the first post, on the first page of this thread. Please read this safety warning before experimenting with any alternative routes of administration of kambo, such as snorting kambo.

You can read this safety warning HERE

Scroll down to the end of that first post to see the safety warning.


33
Application / Re: Kambo Snuff
« on: December 17, 2012, 02:23:43 PM »
Does anybody have recommendations for maximum dosage? (I'll looking for a full and optimal experience, but of course to still keep it safe.) I'm thinking of starting with 15-20mg and working my way up. The thing is there's fear about going too high, and then when tolerance kicks in I'll be going even higher and I'm not sure if the safety of a dosage considers this tolerance, if that makes any sense.

I'd like to know this too:

• What is the dose (in mg) of intranasal kambo required for the full kambo effects (including vomiting and diarrheal bowel evacuation)?

• And what is the maximum safe intranasal kambo dose that you can take?

• At what dose level does kambo start to become dangerous?

• And what are the signs and symptoms of kambo overdose?

Does anyone have any information on this?

Romanesco said (on page 1 of this thread) that the 15 mg of kambo powder he took intranasally didn't quite give the full kambo experience: this amount gave him the swollen face, nausea, diarrhea, but no vomiting. He said that each time he repeated this, it was the same: he just did not vomit. So it may be that you need to take a slightly higher dose, say 20 mg, in order to get the full kambo experience, including vomiting.

Or it may be that phyllomedusin, one of the active constituents of kambo that contributes to violent purging, is not so readily absorbed via the intranasal route.

34
Application / Re: Kambo Snuff
« on: December 16, 2012, 02:41:19 PM »
Some Notes on Weighing Small Quantities of Kambo for Intranasal Administration (Snorting Kambo into The Nose)

The quantity of kambo used in one application is very small: from 15 mg or higher for a full kambo experience, and around 1 to 2 mg of kambo if you want just a very, very mild effects.

This means if you are going to scrape off the kambo substance from the kambo stick (as described in the above post), and take it intranasally, you need a precise method of measuring out your kambo.

The best way is using a sensitive digital scales that weighs down to 1 mg (= 0.001 grams). You can buy such a sensitive digital scales surprisingly cheaply from China or Hong Kong on eBay, for as little as $15 including shipping. See here. This is where I bought mine, and I am very pleased with it.

To increase the accuracy of weighing out kambo powder on a digital scales, I found it is best to mix your whole batch of kambo powder with some "filler" powder like say glucose powder, using a ratio of say 1 part kambo powder, to 4 parts filler powder. That way, each 5 mg of your powder mixture contains 1 mg of kambo.

Then if you want to experiment with very low 1 mg doses of kambo like I do, you just weigh out 5 mg of your powder mixture, which will contain 1 mg of kambo.

If you want to go for a full kambo experience, which starts at doses around 15 mg or so of kambo, then you would weight out 75 mg of your powder mixture to get 15 mg of pure kambo.


35
Application / Kambo Snuff
« on: December 16, 2012, 04:21:05 AM »
TAKING VERY LOW DOSE KAMBO INTRANASALLY (SNORTING)
Exact Method Explained




UPDATE (Feb 2013): The warning posted by KP, about the fact that snorting kambo can lead cause what the Indian's call "frog's disease", is one that should be considered.

UPDATE (May 2013): The following information about catching frog's disease from snorting/sublingual kambo was posted by Galega:


Frog disease is a viral type illnes that cannot be gotten rid of. It is unknown to the outside world. Amongst other things, it can apparently weaken the heart muscles and cause cardiac arrest and have some effects on the brain - he described it as 'eating the brain'!. Indians who snort snuff with kambo in it do so only very occasionally and always in conjunction with heavy kambo sessions so the live kambo acts as a kind of anti venom/viral. Even so, it is still considered risky he says and only for those with strong hearts and systems (eg, regular kambo users). His view is that kambo taken orally could also cause the same problem.



I have just tried some very low dose (1 mg) intranasal kambo (that is, kambo powder snorted up into my nose), and it worked very well.

Here are the details of the method I used to take kambo intranasally. It is described step by step, so that a beginner might follow it.

I bought a kambo stick from Maya Ethnobotanicals. This kambo stick is a flat and thin piece of wood, about 2 mm thick, 25 mm wide, and around 110 mm long. This wooden kambo stick is wrapped in a dark brown corn leaf for protection.

This stick had the kambo substance — that is, the dried slime from the skin of the Phyllomedusa bicolor frog — stuck to it all along one of its flat sides. The kambo substance itself looks like a thick layer of clear vanish on this piece of wood.

I scrapped off about one sixth of the kambo substance from the side of the kambo stick, by means of a sharp knife. I weighed the kambo I had just scrapped off using a digital scales, and it amounted to around 80 mg (which means in the whole kambo stick, you get about 6 x 80 = 480 mg of pure kambo).

I then finely ground up the kambo I had scrapped off using a mortar and pestle (it was already powdery after being scrapped off the stick, but I wanted the powder to be as fine as possible, to ensure good absorption when snorted into my nose).

A full kambo experience (which is always accompanied by vomiting and diarrhea) will probably require slightly more than 15 mg of intranasal kambo powder (see Romanesco's posts earlier in this thread).

However, I want to use a very low daily kambo dose of around 1 mg. This is a very small quantity to measure accurately, even on a digital scales like mine that measures down to 1 mg. So, to my 80 mg of kambo powder, I added 4 x 80 = 320 mg of an inert "filler" powder. I used a vitamin powder I happened to have as my filler powder. I tested this vitamin powder in my nose first, to make sure it did not sting on snorting it (don't use any acidic-tasting powder like vitamin C as a filler, as acidic powders will sting like hell in the nose). Something like glucose powder would work too.

I thoroughly mixed my 320 mg of filler powder with my 80 mg of kambo powder to make a weakened kambo mixer. With my mixture, 5 mg of the mixture powder contains 1 mg of pure kambo.

I weighed 5 mg of my mixture powder on the digital scales, to get a dose of 1 mg of kambo.

I then simply used a drinking straw to snort this 5 mg of mixture powder into one nostril.

Within about a minute, I started to feel tingling effects in my nose. After around 2 minutes or so, my face and all the skin on my body went bright red, as blood was flushed to the surface. (This red flushing of the skin looked very similar to a "niacin flush", if anyone is familiar with that). My heart rate went up a little, but not that much. There was no dizziness. There was no face or throat swelling at all. The effects lasted for less than 5 minutes, before the flushed skin and the raised heart beat went back to normal. It was an extremely mild experience, and it evoked no fear or apprehension at all. Anyone could do this very light dose.

At this very low dose of 1 mg of kambo, I only felt only the very slightest sense of nausea, and I had only a very slight sense of rumbling or movement in my bowels. But I was nowhere near getting sick, or needing to defecate, both of which normally happen on a full dose of kambo.

No mental state changes occurred at all during my experience: I remained calm, focused and unchanged mentally throughout. That is to say, there were no psychoactive effects at all.

My nasal cavity was very slightly sore afterwards, for several hours; but was fine by the next day. I have read elsewhere that people snorting kambo sometimes find it burns the nose a little. At the very low 1 mg dose I used, the soreness was very slight, but I expect higher doses of kambo may produce a little more nasal soreness.


What I am going to do in the near future is try a slightly higher intranasal dose, but I have no intention of doing a full kambo dose just yet.

The reason I am trying out kambo is that I hope it will treat my chronic fatigue syndrome (CFS). Kambo has significanlty improved Jox's chronic fatigue syndrome: see Jox's forum threads on how he used kambo to treat his CFS. So I am hoping kambo will also help my CFS.

What I plan to do is take a very low kambo dose (1 to 2 mg) each day, rather than the full kambo dose that Jox regularly takes once every 7 days, in order to treat his CFS.

I am hoping my very low dose daily kambo regimen will effectively treat my CFS.

If this very low dose kambo regimen does not improve my chronic fatigue syndrome symptoms, then I will try going up to a full dose taken once a week, as per Jox. However, I will still probably use the intranasal method for taking kambo, even for the full dose, as the intranasal approach seems really quick, easy and straightforward to do. But if this full dose intranasal method does not improve my CFS either, will I then consider using the burn method.

One final point: I tried taking very low dose (2 mg) kambo sublingually (under the tongue) on several occasions, but this did not work at all. So for some reason, it seems the mucous membranes of the nasal cavity absorb kambo rapidly and effectively, but the mucous membranes under the tongue do not.

——————————————————————————
Safety Warning
——————————————————————————

Warning: There have been accounts of incorrect use of kambo leading to death.


To quote a Machineri Indian: "Our healers know how to use the frog's secretion. Now, it is being used in other places incorrectly, and this has led to the death of patients." Reference: here.

This should sound a strong warning to anyone considering experimenting with alternative routes of administration of kambo: you may be entering uncharted and risky territory.

Though I have been unable to find the particular details on why these deaths occurred, my guess is that these fatalities may have been caused by accidentally administering too much kambo.

Anyone who is going to experiment with alternative routes of kambo administration, such as the intranasal route, should buy a sensitive digital scales that measures down to 1 mg (= 0.001 grams) before they begin any experimentation, in order to measure doses accurately. You can buy such a scales for as little as $15.

If you don't feel confident about your ability to precisely weigh out tiny milligram amounts of kambo in an accurate manner, then you should not experiment with alternative routes route of kambo administration.

This is because, when using alternative routes of administration, there may be a very real danger of an overdose of kambo if you do not measure your kambo dosage precisely, using a sensitive digital scales that can weigh down to 1 mg.

Kambo contains the highly potent opioid compounds dermorphin and deltorphin. Dermorphin is 30 to 60 times more potent than morphine when taken orally, and 200 to 300 times more potent when taken intravenously. (As little as 200 mg of morphine can be fatal.) Just 1 mg of intravenous dermorphin will kill you instantly. Reference: Exotic Frog Drug Boosting Racing Horse’s Performance.

One might assume that the potency of dermorphin taken intranasally will be somewhere in between its oral and intravenous potency; so one might hazard a guess that intranasal dermorphin is say 100 times more potent than morphine. Therefore, as a rough guess, perhaps around 3 mg of dermorphin taken intranasally would kill you instantly. This is just to give a very rough idea of how tiny the lethal dose of dermorphin is.

I could not find any figures for the percentage dermorphin content of kambo, but if we knew this, we could work out what the lethal dose of intranasal kambo is, from the dermorphin perspective at least.

If you read this account by a person named "SuperJunky" injecting himself with pure dermorphin, you will see he used a tiny dose of 100 micrograms of dermorphin, and found this was as powerful as heroin. Dermorphin is extremely potent stuff.

The deltorphin component of kambo is another issue, as are its other active constituents.

So be very careful with measuring out your kambo doses, if you decide to experiment with taking kambo by alternative routes, such as the intranasal route.

Remember, when you are using the normal burn method of administration of kambo, this burn method has a built-in safety mechanism, in that each burn area will I think only absorb a limited amount of kambo. So I would think you cannot easily overdose with the burn method, because the total kambo dose administered is related to the number and size of the burn areas you make and use.

By contrast, if you are taking kambo powder by alternative routes, such as snorting it into the nose, there is no safety mechanism at all that prevents you from taking too much kambo, because everything you snort into your nose will be absorbed by the nasal mucous membranes. So it is entirely up to you to precisely measure the dose you take, and make sure you don't administer yourself a lethal dose.

Therefore, it is crucial to weigh the exact amount kambo powder in milligrams before you snort it. 

It may well be that doses of 50 to 100 mg of kambo powder taken intranasally might be a lethal for some people. But this is purely a guess, because we don't know the lethal dose of kambo; we need to find some reliable info on this. It seems that 15 mg of pure kambo powder taken intranasally is a tried and tested dose for one person: Romanesco has taken this 15 mg dose level several times intranasally (see his posts on page 1 of this thread). But going much beyond that dose is probably not advisable. This reference provided by KP on page 1 of this thread says the Kaxinawa Indians snort Kambo as a snuff, but the this reference does not provide dosing information.

Finally, if you are going to experiment with alternative routes of administration of kambo, such the intranasal method, remember to observe the normal preparations before taking a full dose of kambo, which requires being on diet without solids or salt for at least 12 hours. Reference: Kambô, The Spirit of the Shaman.


36
Journals / Ordeals / Re: First XXX
« on: December 04, 2012, 09:06:20 PM »
Many thanks, Kambogahuasca.

37
Journals / Ordeals / Re: First XXX
« on: December 04, 2012, 08:28:38 PM »
HI Jox

Any updates on your use of kambo for treating your chronic fatigue syndrome?

Is kambo still providing benefits for your CFS symptoms?

38
I love the burning application and consider it unsurpassable technology.  I want to put other things in the burns too, as I have heard the Matses use other medicines in that way.  Iboga TA to the burn???  I'll find out within the year.

One unconfirmed thing I read was that it is not actually the burn itself that allows the kambo peptides to enter the body, but rather the local inflammatory response that kicks into action at the burn site. Though I have not seen any solid references for this, so it remains unconfirmed in my mind.

If true, though, it suggests that kambo could be administered via other types of inflammatory skin responses, like say a nickel contact allergy on the skin (for those allergic to nickel: 17% of women and 3% of men are allergic to nickel).


 

39
One thought: might there be a danger of taking too much kambo if you administer it via the mucous membranes?

Might the main purpose of the skin burning administration used by the Amazonian Indians in fact be to precisely control the kambo dose?

Perhaps on small areas of burnt skin, only a controlled and consistent amount of kambo is absorbed. Even if you were to place much higher amounts of kambo on the burn skin area, this may not substantially increase the dose you receive (but I am just guessing). In other words, the skin burning administration of kambo used by the Amazonian Indians might actually be done for safety, in order to prevent accidental overdose, and in order to achieve consistent dosing.

But with administration through the mucous membranes (nasal cavity, mouth, etc), perhaps if you were to accidentally apply a very high amount of kambo in this way, most of this kambo might be absorbed, giving you an overdose.

Consider that, if kambo can be easily administered via the mucous membranes where it is well absorbed, there must be a good reason why these Amazonian Indians choose to use the more complex skin burning approach, instead of just say snorting kambo into the nose, or just smearing kambo onto the upper gums. My guess is that they employ the skin burning administration because helps to deliver a controlled, consistent dosage.

Of course, with precise digital scales, you may be able to measure the correct and consistent dose for mucous membrane administration — provided that your source of kambo does not vary much in its concentration.

I just mention all this, because it is important to consider safety.

For microdosing kambo, obviously there is not so much concern about taking a little too much, as you are only using small doses anyway.





40
Sorry about that.  So right around :40-1:30

http://www.youtube.com/watch?v=tlrk3GoHG3w&feature=plcp&context=C3bb00b9UDOEgsToPDskKjV-yywwYr3DybvVdHZrsN

Also Gloriadeo microdoses with Kambo.  I plain on doing 1 per day for 7 days here soon and I will let you know it goes.

Thanks KP. So the guy in the video got some kambo in his eye while handling the frog, and this produced a full kambo experience.  Wow.

I guess that makes sense, though, since the eye socket and inner eye lid is a mucous membrane, so would likely absorb kambo just as well as the mucous membrane in the nasal cavity.

I am thinking that smearing kambo with your finger all around the gum area above your upper teeth should also be effective — and is very easy to do. 


41
Kambo eye drops...
Check this video out and listen very close to seconds 40 through minute 1:35

http://www.youtube.com/watch?v=tlrk3GoH ... ybvVdHZrsN

I will be doing this soon, trust me it is safe and will be visionary.  Sananga just told me so.  Mega dilluted in between a homeopathic and a regular recipe with some MSM and Neti Salt. 


Sounds very interesting, KP, though the youTube weblink given does not work — could you post this link again please.

42
Thanks very much Kambogahuasca Panacea and Romanesco for your replies.

Regarding the 15 mg of dried kambo secretions, scrapped from the kambo stick and snorted into the nose: is this amount enough to produce the full kambo experience — ie, nausea, vomiting and diarrhea for 30 minutes — that you get using the skin burn method of kambo administration? Or does snorting 15 mg of dried kambo produce a much milder effect?

I would also like to know if anybody has microdosed kambo, taking small daily kambo doses that produce very few symptoms, rather than taking one full kambo dose every month that produces strong symptoms.

If microdosing very small daily amounts of kambo (via snorting, or perhaps sublingually) provides the same health and curative benefits as a single strong monthly dose, then this microdosing might be an easier way of taking kambo (especially for people like me that have chronic fatigue syndrome or other health conditions, who don't quite feel fit enough to go through the intense experience you get with the full kambo dose).




43
Journals / Ordeals / Re: First XXX
« on: May 18, 2012, 12:29:16 AM »
Very interesting post, Jox.

I also have chronic fatigue syndrome, and I am thinking of trying kambo for my CFS. I am not bedbound, but semi-housebound due to my CFS.

My worst symptoms are: brain fog, memory problems, anxiety, ADHD-like symptoms, emotional flatness, strong anhedonia, and sometimes some mild depression.

Do you have similar symptoms, and if so, has kambo helped these symptoms?

44
New Ways of Administering Kambo?



UPDATE (Feb 2013): The warning posted by KP, about the fact that snorting kambo can lead cause what the Indian's call "frog's disease", is one that should be considered.

UPDATE (May 2013): The following information about catching frog's disease from snorting/sublingual kambo was posted by Galega:


Frog disease is a viral type illnes that cannot be gotten rid of. It is unknown to the outside world. Amongst other things, it can apparently weaken the heart muscles and cause cardiac arrest and have some effects on the brain - he described it as 'eating the brain'!. Indians who snort snuff with kambo in it do so only very occasionally and always in conjunction with heavy kambo sessions so the live kambo acts as a kind of anti venom/viral. Even so, it is still considered risky he says and only for those with strong hearts and systems (eg, regular kambo users). His view is that kambo taken orally could also cause the same problem.
http://kambo.me/smf/index.php?topic=52.msg1395#msg1395



I am interested in discussing/innovating new methods of administering kambo (other than the traditional method of mildly burning small areas on the skin with hot smoldering ash, and then putting kambo on the burnt skin where it is absorbed transdermally at the burn).

What other ways might there be to absorb a dose of kambo?

Well, I believe that the peptides in kambo readily cross the mucous membranes, since I have read reports of people successfully administering kambo intranasally (ie, snorting kambo into the nose). The nasal cavity is lined with a mucous membrane, and this is where the kambo would be absorbed. Mucous membranes are far more absorbent than normal skin.

Furthermore, there are several other useful mucous membranes to be found on the body, which should also absorb kambo. These mucous membranes include: the lining within the mouth, and the lining in the rectum.

I think it is these various mucous membrane areas that are most likely to facilitate successful kambo absorption.

There are also some normal skin areas that are more permeable than others, such as the skin of the scrotum, and to a lesser degree, the perhaps skin under the armpits. Many substances are absorbed transdermally through the skin, which is why you can get nicotine patches, testosterone patches, and so forth. However, my guess is these skin areas will not work for kambo.

Anyway, to get this discussion going, below is a list of places on the skin and the mucous membranes where kambo might well be absorbed.

Note that in any experiments on these areas of skin and mucous membrane, it is important to be cautious, and initially begin using a very low dose of kambo, just in case the method you use absorbs more kambo than you anticipated.


List of Experimental Kambo Administration Areas / Techniques

Mucous Membrane Areas:
 
Intranasal. Snorting up kambo powder via a drinking straw through the nose and into the nasal cavity, where there is a large mucous membrane. Test a small amount of powder in the nose first, to ensure it does not sting.

Note: for intranasal kambo insufflation (snorting kambo powder as snuff), see also this thread on taking kambo snuff.
 
On upper gums. There is a reasonably large area of mucous membrane on the upper gums (above your upper teeth) and on the inner cheeks inside the mouth that may well absorb kambo. You could put some kambo on your finger tip, and massage it on your upper gum area. Lower gum area may also work, but there is more saliva in the lower gum area that may wash away the kambo before it gets the chance to absorb.

Sublingual. The mucus membranes under the tongue and on the lower floor of the mouth may well absorb kambo. You could put some kambo on your finger tip, and massage it into these mucous membranes for a few minutes (the massage should mechanically aid absorption). Though again, saliva may wash away the kambo before it has a chance to absorb through these sublingual mucous membranes.

Intraurethral. Not for the faint hearted! The skin lining the urethra is a mucous membrane. The male urethra is around 18 cm long; the female urethra is around 4 cm long. Sounds possibly painful to administer here, but note that the urethral mucous membranes are not quite as sensitive as the nasal mucous membranes.

Glans and foreskin. The glans of the penis is a mucous membrane, and the inner foreskin is a mucous membrane (the outside of the foreskin is a continuation of the skin on the shaft of the penis, but the inner foreskin is a mucous membrane).
 
Intravaginal pessary. Such pessaries are a well-known and highly effective means of absorbing drugs or supplements.
 
Rectal suppository. Conceivably, the correct dose of kambo could be placed in the rectum as a suppository capsule. The rectum is lined with a mucous membrane (and this rectal mucous membrane is larger in area than the mucous membrane of the nasal cavity).

 
Skin Areas:
 
Transscrotal absorption. Whilst the scrotum is not a mucous membrane, it is more absorbent than other skin sites. Transscrotal absorption is employed by some transdermal testosterone patches, and scrotal skin permits 5 to 40 times greater absorption of testosterone than other skin sites. Perhaps kambo might be absorbed here?
 
Under armpits and underside of arms. The skin here is thinner and more absorbent than other areas of body skin. A shaved armpit is useful here.

Sonophoresis. Sonophoresis is a standard technique for increasing the transdermal absorption of vitamins, drugs and other compounds through the skin. Sonophoresis uses the ultrasonic vibrations of a small metal plate to push vitamins and drugs through the skin. Ultrasonic massagers which have a vibration frequency from 1 to 3 megahertz (MHz) can be used to perform sonophoresis. These ultrasonic vibrations cause temporary microscopic pores to open in the skin, which help the skin absorb compounds.
 
——————————————————————————
Safety Warning
——————————————————————————

Warning: There have been accounts of incorrect use of kambo leading to death.


To quote a Machineri Indian: "Our healers know how to use the frog's secretion. Now, it is being used in other places incorrectly, and this has led to the death of patients." Reference: here.

This should sound a strong warning to anyone considering experimenting with alternative routes of administration of kambo: you may be entering uncharted and risky territory.

Though I have been unable to find the particular details on why these deaths occurred, my guess is that these fatalities may have been caused by accidentally administering too much kambo.

Anyone who is going to experiment with alternative routes of kambo administration, such as the intranasal route, should buy a sensitive digital scales that measures down to 1 mg (= 0.001 grams) before they begin any experimentation, in order to measure doses accurately. You can buy such a scales for as little as $15.

If you don't feel confident about your ability to precisely weigh out tiny milligram amounts of kambo in an accurate manner, then you should not experiment with alternative routes route of kambo administration.

This is because, when using alternative routes of administration, there may be a very real danger of an overdose of kambo if you do not measure your kambo dosage precisely, using a sensitive digital scales that can weigh down to 1 mg.

Kambo contains the highly potent opioid compounds dermorphin and deltorphin. Dermorphin is 30 to 60 times more potent than morphine when taken orally, and 200 to 300 times more potent when taken intravenously. (As little as 200 mg of morphine can be fatal.) Just 1 mg of intravenous dermorphin will kill you instantly. Reference: Exotic Frog Drug Boosting Racing Horse’s Performance.

One might assume that the potency of dermorphin taken intranasally will be somewhere in between its oral and intravenous potency; so one might hazard a guess that intranasal dermorphin is say 100 times more potent than morphine. Therefore, as a rough guess, perhaps around 3 mg of dermorphin taken intranasally would kill you instantly. This is just to give a very rough idea of how tiny the lethal dose of dermorphin is.

I could not find any figures for the percentage dermorphin content of kambo, but if we knew this, we could work out what the lethal dose of intranasal kambo is, from the dermorphin perspective at least.

If you read this account by a person named "SuperJunky" injecting himself with pure dermorphin, you will see he used a tiny dose of 100 micrograms of dermorphin, and found this was as powerful as heroin. Dermorphin is extremely potent stuff.

The deltorphin component of kambo is another issue, as are its other active constituents.

So be very careful with measuring out your kambo doses, if you decide to experiment with taking kambo by alternative routes, such as the intranasal route.

Remember, when you are using the normal burn method of administration of kambo, this burn method has a built-in safety mechanism, in that each burn area will I think only absorb a limited amount of kambo. So I would think you cannot easily overdose with the burn method, because the total kambo dose administered is related to the number and size of the burn areas you make and use.

By contrast, if you are taking kambo powder by alternative routes, such as snorting it into the nose, there is no safety mechanism at all that prevents you from taking too much kambo, because everything you snort into your nose will be absorbed by the nasal mucous membranes. So it is entirely up to you to precisely measure the dose you take, and make sure you don't administer yourself a lethal dose.

Therefore, it is crucial to weigh the exact amount kambo powder in milligrams before you snort it. 

It may well be that doses of 50 to 100 mg of kambo powder taken intranasally might be a lethal for some people. But this is purely a guess, because we don't know the lethal dose of kambo; we need to find some reliable info on this. It seems that 15 mg of pure kambo powder taken intranasally is a tried and tested dose for one person: Romanesco has taken this 15 mg dose level several times intranasally (see his posts on page 1 of this thread). But going much beyond that dose is probably not advisable. This reference provided by KP on page 1 of this thread says the Kaxinawa Indians snort Kambo as a snuff, but the this reference does not provide dosing information.

Finally, if you are going to experiment with alternative routes of administration of kambo, such the intranasal method, remember to observe the normal preparations before taking a full dose of kambo, which requires being on diet without solids or salt for at least 12 hours. Reference: Kambô, The Spirit of the Shaman.


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