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Messages - ―λlτεrηιτγ-

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1
Exercise / Bodybuilding / Re: Increasing Human Growth Hormone
« on: February 06, 2020, 04:01:10 pm »
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Glutamine and glutamate with proline, histidine, arginine and ornithine, comprise 25% of the dietary amino acid intake and constitute the "glutamate family" of amino acids, which are disposed of through conversion to glutamate. Although glutamine has been classified as a nonessential amino acid, in major trauma, major surgery, sepsis, bone marrow transplantation, intense chemotherapy and radiotherapy, when its consumption exceeds its synthesis, it becomes a conditionally essential amino acid. In mammals the physiological levels of glutamine is 650 micromol/l and it is one of the most important substrate for ammoniagenesis in the gut and in the kidney due to its important role in the regulation of acid-base homeostasis. In cells, glutamine is a key link between carbon metabolism of carbohydrates and proteins and plays an important role in the growth of fibroblasts, lymphocytes and enterocytes. It improves nitrogen balance and preserves the concentration of glutamine in skeletal muscle. Deamidation of glutamine via glutaminase produces glutamate a precursor of gamma-amino butyric acid, a neurotransmission inhibitor. L-Glutamic acid is a ubiquitous amino acid present in many foods either in free form or in peptides and proteins. Animal protein may contain from 11 to 22% and plants protein as much as 40% glutamate by weight. The sodium salt of glutamic acid is added to several foods to enhance flavor. L-Glutamate is the most abundant free amino acid in brain and it is the major excitatory neurotransmitter of the vertebrate central nervous system. Most free L-glutamic acid in brain is derived from local synthesis from L-glutamine and Kreb's cycle intermediates. It clearly plays an important role in neuronal differentiation, migration and survival in the developing brain via facilitated Ca++ transport. Glutamate also plays a critical role in synaptic maintenance and plasticity. It contributes to learning and memory through use-dependent changes in synaptic efficacy and plays a role in the formation and function of the cytoskeleton. Glutamine via glutamate is converted to alpha-ketoglutarate, an integral component of the citric acid cycle. It is a component of the antioxidant glutathione and of the polyglutamated folic acid. The cyclization of glutamate produces proline, an amino acid important for synthesis of collagen and connective tissue. Our aim here is to review on some amino acids with high functional priority such as glutamine and to define their effective activity in human health and pathologies.

https://www.ncbi.nlm.nih.gov/pubmed/12481981

2
Supplements / Lithium
« on: January 19, 2020, 06:27:46 pm »
Oxidative metabolism
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Evidence suggests that mitochondrial dysfunction is present in patients with bipolar disorder.[72] Oxidative stress and reduced levels of anti-oxidants (such as glutathione) lead to cell death. Lithium may protect against oxidative stress by up-regulating complex I and II of the mitochondrial electron transport chain.

Dopamine and G-protein coupling
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During mania, there is an increase in neurotransmission of dopamine that causes a secondary homeostatic down-regulation, resulting in decreased neurotransmission of dopamine, which can cause depression.[72] Additionally, the post-synaptic actions of dopamine are mediated through G-protein coupled receptors. Once dopamine is coupled to the G-protein receptors, it stimulates other secondary messenger systems that modulate neurotransmission. Studies found that in autopsies (which do not necessarily reflect living people), people with bipolar disorder had increased G-protein coupling compared to people without bipolar disorder.[72] Lithium treatment alters the function of certain subunits of the dopamine associated G-protein, which may be part of its mechanism of action.

Glutamate and NMDA receptors
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Glutamate levels are observed to be elevated during mania. Lithium is thought to provide long-term mood stabilization and have anti-manic properties by modulating glutamate levels.[72] It is proposed that lithium competes with magnesium for binding to NMDA glutamate receptor, increasing the availability of glutamate in post-synaptic neurons.[72] The NMDA receptor is also affected by other neurotransmitters such as serotonin and dopamine. Effects observed appear exclusive to lithium and have not been observed by other monovalent ions such as rubidium and caesium.

GABA receptors
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GABA is an inhibitory neurotransmitter that plays an important role in regulating dopamine and glutamate neurotransmission.[72] It was found that patients with bipolar disorder had lower GABA levels, which results in excitotoxicity and can cause apoptosis (cell loss). Lithium has been shown to increase the level of GABA in plasma and cerebral spinal fluid.[74] Lithium counteracts these degrading processes by decreasing pro-apoptotic proteins and stimulating release of neuroprotective proteins.[72] Lithium's regulation of both excitatory dopaminergic and glutamatergic systems through GABA may play a role in its mood stabilizing effects.

Cyclic AMP secondary messengers
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Lithium's therapeutic effects are thought to be partially attributable to its interactions with several signal transduction mechanisms.[76][77] The cyclic AMP secondary messenger system is shown to be modulated by lithium. Lithium was found to increase the basal levels of cyclic AMP but impair receptor coupled stimulation of cyclic AMP production.[72] It is hypothesized that the dual effects of lithium are due to the inhibition of G-proteins that mediate cyclic AMP production.[72] Over a long period of lithium treatment, cyclic AMP and adenylate cyclase levels are further changed by gene transcription factors.

Inositol depletion hypothesis
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Lithium treatment has been found to inhibit the enzyme inositol monophosphatase, involved in degrading inositol monophosphate to inositol required in PIP2 synthesis. This leads to lower levels of inositol triphosphate, created by decomposition of PIP2.[78] This effect has been suggested to be further enhanced with an inositol triphosphate reuptake inhibitor. Inositol disruptions have been linked to memory impairment and depression. It is known with good certainty that signals from the receptors coupled to the phosphoinositide signal transduction is affected by lithium.[79] myo-inositol is also regulated by the high affinity sodium mI transport system (SMIT). Lithium is hypothesized to inhibit mI entering the cells and mitigating the function of SMIT.[72] Reductions of cellular levels of myo-inositol results in the inhibition of the phosphoinositide cycle.

https://en.wikipedia.org/wiki/Lithium_(medication)#Glutamate_and_NMDA_receptors

3
General Discussion / Kambo.me URL working again.
« on: January 19, 2020, 05:18:30 pm »
Kambo.me URL is working again.

4
Video / Desert Seas
« on: January 18, 2020, 02:04:10 am »

5
Video / Mucky Secrets (Documentary)
« on: January 18, 2020, 02:01:20 am »
Let's bring in some nature documentaries.

Mucky Secrets (Documentary)

https://www.youtube.com/watch?v=nJMZ6reOB0E

7
Dry Fasting / Re: Deep waters
« on: January 09, 2020, 02:25:50 pm »
Do you still shower bath regularly while dry fasting? Or avoid it till allowing yourself to take in water again?


One thing that comes to mind is to add a note of caution to those that might have kidney issues.


"In patients with stage 3 or higher CKD, Ramadan fasting during the summer months was associated with worsening of renal function. Clinicians need to warn CKD patients against Ramadan fasting."

"During Ramadan, Muslims must abstain from eating or drinking from dawn to sunset every day for a whole month." ... "the duration of fasting varies from 12-18 hours" ... "Although there is an exemption from fasting provided to sick people, many of these patients wish to fast. Physicians in Muslim countries are frequently consulted by their patients regarding the effects of fasting on their health, including patients with chronic kidney disease (CKD). Although many studies have shown that fasting during Ramadan has no adverse effect on healthy people, the few studies that have been conducted on the effect of Ramadan in patients with CKD have found inconsistent results. Moreover, some of these studies were conducted during the winter season, and others were conducted during the summer time. Therefore, we carried out this study on the effect of Ramadan fasting on worsening of renal function (WRF) in patients with more advance CKD during the period in summer with the longest days."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278065/

9
Women's Health / Re: Know About Women's Dental Health
« on: January 08, 2020, 09:07:08 am »
Hey Ferber20,

I see you've lurked the forum for a while. Let me give you a late but warm welcome, since I hadn't yet.
I've added so many additional choice sections and subsections to the forum,
and hope to see users contribute to them and appreciating and benefiting from them.
Sending some good karma your way through the forum feature for contributing to a newer section of the forum =)

I've been using a brand of toothpaste called Desert Essence.
The specific one is "Natural Tea Tree Oil & Neem Toothpaste - Wintergreen
with Baking Soda & Essential Oil of Wintergreen - Flouride and SLS (Sodium Laurel Sulfate).
I have a soap dispenser, also on the sink which I fill with either Dr. Bronner's natural soap or Sun & Earth brand.
(Both derived from natural plant oils or plant oil constituents)
I mix 1/3rd part soap and 2/3rds part water, and I'll usually add a couple drops onto the brush as well.

I use natural bamboo toothbrushes with charcoal bristles, which are really cheap on eBay.
As to avoid unnecessary plastic products. Plus I think they're badass.

After brushing I use a copper (anti-microbial) tongue scraper, and scrape down, from the back of the tongue.
https://en.wikipedia.org/wiki/Antimicrobial_properties_of_copper
That I purchased packs of, off of eBay. I believe there's at least 2 popular metals used that you can purchase.
It's an Ayurvedic traditional Indian medicine practice; And there's specific metals recommended for different Ayurvedic dominant doshas.
I believe Stainless Steel, also anti-microbial, is the one recommended for my Pitta dominant dosha.

Just like in Auriculotherapy, Reflexology, Facial Acupucture - how ears, feet, hands, and face are microcosms of the body -
tongue scraping is supposed to help detoxify and refresh the organs of the body.

See here, as the forum only lets me embed images with a small file size, within the post.
https://www.yogadownload.com/Portals/0/Images2/Blog%20Thumbnails/605c1c60-92bf-40ff-85fa-243d79a2497f.jpg

Then I use a neti pot to clean my nose and sinuses, helping clear the respiratory tract.
And gargle with the remaining warm water and sea salt.

Therapeutic grade Clove essential oil is also greatly beneficial as a local anesthetic.
I've purchased it cheaply off of eBay, and had it shipped to a friend in the past, who was suffering from not having health insurance.

Also, White Oak bark is a strong astringent and helps tighten and strengthen the gums. You can kind of suck on it and gently chew it, without the intention of breaking it apart.
https://brigittemars.com/articles/herbal-natural-remedies/natural-toothcare/

There's also an herb called Toothache Plant (Acmella oleracea), which was used by Native Americans.

Zanthoxylum clava-herculis, along with the related Zanthoxylum americanum, it is sometimes called "toothache tree"[3][4] or "tingle tongue" because chewing on the leaves, bark, or twigs causes a
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tingling numbness of the mouth, tongue, teeth and gums. It was used for such medicinal purposes by both Native Americans and early settlers to treat toothache because of this.
https://en.wikipedia.org/wiki/Zanthoxylum_clava-herculis

I believe chewing on the root or stem of Echinacea would work the same way. As well as being anti-mocrobial, it causes numb tingling in the mouth.

They can be used as aphrodisiacs and sucked and chewed on before oral sex, because of those properties, namely the electric tingling feeling.  ;D

And as much of a naturalist as I am, I agree with seeing your dentist when due if you have the means, especially if you benefit from having health insurance.

Best regards

10
Kambo & Other Sacraments / Re: A New Paradigm: Tobacco Disinformation
« on: January 04, 2020, 08:04:19 am »
Ohm brand tobacco. They are additive free except for "flavoring agents".
It's Windy City Cigars brand. Whom I always order from.
https://windycitycigars.com/brands/ohm-tobacco/

I used to order from Kentucky Select. They were an FDA certified Organic but they could no longer keep up with the extra FDA fees to keep the FDA Organic label.
So they went additive free - from what I read in a blog - that they still treated their farm as organic but just couldn't afford the labeling.
When I check their products now, they have one bag / flavor they call "Natural"; So I've just switched to Ohm tobacco because they specifically say it's all additive free

11
Introductions / Re: Newbie from Switzerland
« on: December 27, 2019, 02:34:39 pm »
You are very welcome! =)

12
General Discussion / Re: Question of safety // Blood-brain barrier
« on: December 13, 2019, 06:21:44 am »
Glad you enjoy it. A lot of thought has gone into it. =)

13
Introductions / Re: Newbie from Switzerland
« on: December 12, 2019, 09:27:37 am »
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so on the initiation side it's good but no answer as to my questions...
maybe not the right section but I wanted to enjoy putting all my questions in the same place...

Hello, welcome to the community! Sorry the forum is a bit slow, especially lately.
With the more advanced users (experienced, have been a member for a while, and readily contribute information when they can) having been absent or not very active.
The latter applies to me as I have not been able to be as active as I'd like to be.
And often when I log in, I spend my time behind the scenes working on the forum itself.
E.g. am looking into purchasing and applying a nice new theme / layout to the forum. I think a dark one would be cool =)
And working with the admin who actually runs our server to try and get the "Kambo.me" base link working again.
If he wasn't so busy, I would try to pay and get the website a TLS certificate - which is why your browser might say "Not secure" before the url in the address bar.
This means there's no encryption from you to the server. Which isn't too important for this site because no one is inputting credit card information, etc.;
And also look into perhaps a .com domain name.


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1. The Ayahuasca I ordered from Maya is a "TA alcohol extract" 10ml tincture equivalent to 300g of vine. I'll take 5ml of it so 150g of vine. I saw that with Kambo you had to remove the alcohol 1 week before... but given the small amount, can this really be a problem? (I will take the Kambo before and after the ceremony).

FYI to anyone who doesn't know, TA = total alkaloid. A shot in the US is usually 30ml, sometimes up to 37ml according to Wikipedia. Perhaps about 40% ethanol (drinkable alcohol).
So you have about a 3rd of a shotglass of alcohol contained in your extract. The proof of the alcohol (percentage), is probably a bit stronger than a normal drink you would shoot. For example, it might be extracted with Everclear at 120, 151, 189, or 190 U.S. proof (60%, 75.5%, 94.5% and 95% alcohol by volume, respectively). Proof # = twice the percentage of the alcohol content. The higher the better for an extraction. I use 190 proof, for example, when soaking absinthe herbs and distilling their essential oils (I word it this way because although making absinthe I've not distilled alcohol, the alcohol percentage of the final product is less than the everclear tea I started with so it's really an infusion even though alcohol is run through a still. Nothing illegal.

I would say that this amount of alcohol should not have any noticeable effect on the ayahuasca session. But you could pour it in a metal shot glass for example and put it somewhere warm.
Like an oven set to "warm" with the door open (due to the alcohols aromatizing / evaporation and flammability). You could just put a fan blowing over it to help evaporate it faster. Optimally low heat + fan. Alcohol will evaporate faster than water. Which is why you could add water first and then evaporate. When the liquid gets low, it should be only water left over. That way you wouldn't need to evaporate it into a goop or hard resin to be scraped up into a crystalline powder or whatever it's texture. Adding water will reduce the flammability when working with a heat source.

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2. I normally fast on the day of the ceremony but I saw that with Kambo it is good to eat after... If I do Kambo in the morning and I want to do Kambo again before the Ayahuasca-Mushroom evening ceremony, is it possible to eat just after the morning ceremony, I mean how soon can we eat after the kambo? Any advice on food?

You can eat after kambo, after the nausea subsides and you feel the strength and hunger enough to feel up for it. Afterwards you feel sober but wiped out which is why you may have seen food recommended. You may feel like eating and sleeping immediately after. I would not do kambo in the same day as an ayahuasca ceremony. There are experience reports here of that, and it can be extremely intense with hours of vomiting. Yes, I recommend enemas of herbal tea and clean water before and / or after kambo to help for a deeper cleanse. Before kambo helps the most because it helps to hydrate you from the other end. Your body can absorb a lot of water easily through an enema. More so if the medicines in it are on the gentler side, else your body will be quicker to purge it out the back. Remember that one should be fasted at least 6 hours before taking kambo.

You didn't ask, but I would eat light before ayahuasca and space it out. It is up to you, eating nothing, and you may feel a little shakey and whatnot. I definitely don't recommend eating within an hour of Aya (really any drug) - at least an hour and a half. The best Ayahuasca experience I've had was culminating a 3 day fast of spring water, fresh fruit and vegetable juicing, and herbal tea enemas. I took yagé (Chaliponga + Bannisteriopsis muricata). I had been doing enemas, maybe daily? (I try when fasting) And I think I may have ended the fast with an enema just before the yagé. I do remember though, that instead of nausea with the yagé, it went through me, surprising me that I had anything more to expel.

I see that you are looking for healing but I would not do the aya in the same day as kambo, because of the Bannisteriopsis' purgative / emetic effect.
I once did some dried peyote and methoxetamine at the end of the day after doing kambo in the morning / afternoon and felt amazing. I was at a  lounge (bar / club) with friends with a DJ who was also a friend playing dubstep and drum & bass style music. I felt very clean, inside and out, and light in my body; And like I was resonating at a higher frequency. I felt spiritual like my third eye was open and

Anyway there's infinite medicines you could work with for healing without needing to do those two in the same day. That's my opinion. I want to work with the herb Cleavers together with kambo. Cleavers grows in my backyard and works on the lymph system (which is what kambo does, and why we apply it under the top layer of skin via burns.

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3. I was very interested in the acupuncture mentioned by some of the members here, particularly ear acupuncture... A tip to treat physical fatigue ? I know we could put the Kambo towards the adrenals ? or the meridians but... there are plenty of meridian points to choose from.. ? rather by ear ? If it helps, I often have problems on the right side of my body and I am left-handed.

Ear acupuncture is called auricular acupuncture. Significant because all parts of the body can be stimulated via points on the ear. I believe this is also true of the face, feet and hands. I imagine the ears to be a very uncomfortable place to do kambo. As it feels like the blood is pumping into your head and like blood pressure has gone way up (because you hear your heart beating in your head) and you become red and flushed. My ears having been burnt with kambo applied would probably be too much for me to deal with while undergoing the effects of kambo.

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4. Will it be too strong to start with acupuncture points ?

No, not sure I can really even feel a discernible difference in strength either way. Others report that they do, and that people should do less points.
In the circumstance, if I do less, I won't purge. 6 points is perfect for me with me occasionally needing to force purging with my fingers.
The more hydrated you are the easier the purge will be. Usually 1-2 liters is recommended but I recommend at least 2.

Read this as a cautionary tale about combining kambo and aya: http://kambo.me/smf/index.php?topic=26.0

Hope this helps =)
Glad to have you aboard. Sorry for the delay in receiving a response.
I hope for everyone to have enough patience to stick around, as it would be worthwhile. Sometimes others are quick to help and other times a response may take some time.

14
When new Boards (sections) of the forum are added, the forum does not automatically add the base "membergroup":
"Called By The Medicines", the ability to access them.
Perhaps because when users sign up, they start off in that category and require no posts to access the forum.

What a shame because half the forum or more was blocked to yous.
I just manually added added (checked) that membergroup for access for every board on the forum.
Most all of you will now find a huge amount of new sections / topics.

Go here: http://kambo.me/smf/index.php

And just look while scrolling down. FYI you can customize by collapsing / minimizing sections that you don't visit.

Perhaps the Spanish section will be helpful to many that seem to struggle posting.

Please now - Everyone enjoy the rest of the forum!!

EDIT: Not sure the cause of this, if it was a forum glitch, in which case it should have been fixed.
It doesn't make sense cause even guests can view all the sections. Can anyone that is logged in, confirm that they were effected by this?


15


I have moved posts offering Iboga rootbark, possibly kambo, and etc.; here. I caution that if you attempt a purchase and you take the risk on a loss.
I have no way of knowing legitimacy of vendors.
I appreciate legitimate vendors, and of course we really appreciate anyone offering Iboga who is making sustainability efforts;
And saving all the seeds to grow - and possibly working with cuttings?

Vendors seeking to advertise here should contact me through private message or become familiar to users of this forum.
If vendors are "sponsored" (verified as trustable) by kambo forum via trusted member review/s, meaning permitted, and posted or moved to the "sponsors" section by an admin.
If a vendor is willing to send out a sample so that users can post reviews (provided the material is legal in their country);
We can select trustworthy active members. Chewing iboga rootbark is like tasting a battery (sensation).

In this section the risk is on the buyer in trusting these ads.

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